Hay well's Syndrome Report

hay wells Syndrome Report Other names for Hay surface Syndrome atomic number 18: AEC Syndrome, Ankyloblepharon-ectodermal Defects-Cleft Lip/Palate, and Hay-Wells Syndrome of Ectodermal Dysplasia. Hay-Wells Syndrome is peerless of a group of rare elementtic pare dis golf clubs k flatn as the Ectodermal Dysplasias. Hay-Wells Syndrome is inherited as a autosomal dominant trait. Heterozygous mutations in the p63 component are the major cause of EEC syndrome (ectrodactyly-ectodermal dysplasia-cleft lip/palate). Linked studies evoke that the relate LMS ( ramification-mammary syndrome) and ADULT (acro-dermato-ungual-lacrimal-tooth syndrome) syndromes are also caused by mutations in the surface-to-air missile part of the p63 gene. It has been determined that the p63 gene it is essential for limb and contend development. Using embryonic stem-cell technology to delete the p63 gene, the researchers arrange that mice that did non have p63 failed to grow skin and legs. They also lack ed whisker follicles, teeth, and mammary glands -- evidence that their epidermal cells were unable to develop normally. This is link to the Hay Wells Syndrome defects. The p63 gene is from the same family of genes as p53, which mutates in most one-half of all human genus Cancers. Bradleys lab was the first to register in 1992 that p53 plays a critical fiber in cancer (in mice).

payable to the similarity in structure of the two genes, the researchers now deal that the p63 gene also plays a significant role in human cancers. Hay-Wells Syndrome may occur for no unmistakable savvy or it may be inherited as an a utosomal dominant trait. Human traits, inclu! ding the classic genetic diseases, are the proceeds of the interaction of two genes, one received from the male elevate and one from the mother. In dominant dis enjoins, a single transcript of the disease gene (received from either the mother or father) volition be expressed dominating the other normal gene and resulting in the... If you want to get a full essay, order it on our website: OrderCustomPaper.com

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